esxH , Protein TB10.4 , ESAT-6-like protein EsxH , cfp7 , 10 kDa antigen CFP7 (CFP-7) , Low molecular weight protein antigen 7
EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery.
TMPH-03011
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