PPAR-gamma , pparg , Nuclear receptor subfamily 1 group C member 3 , nr1c3 , Peroxisome proliferator-activated receptor gamma
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
TMPH-03711
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