IgSF16 , Immunoglobulin Superfamily Member 16 , CD300C , CLM-6 , CMRF35A1 , CD300 Antigen-Like Family Member C , CMRF35-Like Molecule 6 , CMRF-35 , CMRF35 , CMRF35A , CMRF35-A1
CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.
Molecular Weight:
60-90 KDa (reducing condition)
TMPJ-00109
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