GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)

Product Overview

• Article Name: GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)
• Biozol Catalog Number: TGM-TMPJ-00290
• Supplier Catalog Number: TMPJ-00290
• Alternative Catalog Number: TGM-TMPJ-00290-1MG,TGM-TMPJ-00290-5UG,TGM-TMPJ-00290-10UG,TGM-TMPJ-00290-20UG,TGM-TMPJ-00290-50UG,TGM-TMPJ-00290-100UG,TGM-TMPJ-00290-200UG,TGM-TMPJ-00290-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: TRNR2 , GDNFR-beta , TGF-beta-related neurotrophic factor receptor 2 , GDNFRB , RET ligand 2 , RETL2 , Neurturin receptor alpha , TGF-beta-related neurotrophic factor receptor 2 , GDNFR-beta , Neurturin receptor alpha

Product Description

GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kinase receptor. It acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.

Images

TMPJ-00290