IFNAR1 Protein, Rhesus macaque, Recombinant (His)

Catalog Number: TGM-TMPJ-00331
Article Name: IFNAR1 Protein, Rhesus macaque, Recombinant (His)
Biozol Catalog Number: TGM-TMPJ-00331
Supplier Catalog Number: TMPJ-00331
Alternative Catalog Number: TGM-TMPJ-00331-1MG,TGM-TMPJ-00331-5UG,TGM-TMPJ-00331-10UG,TGM-TMPJ-00331-20UG,TGM-TMPJ-00331-50UG,TGM-TMPJ-00331-100UG,TGM-TMPJ-00331-200UG,TGM-TMPJ-00331-500UG
Manufacturer: TargetMol
Category: Biochemikalien
Alternative Names: IFN-al , CRF2-1 , IFN-alpha/beta receptor 1 , human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC , alpha-type antiviral protein , AVP , Cytokine receptor family 2 member 1 , IFN-alpha/beta R1 , beta-type antiviral protein , IFN-alpha/beta receptor 1 , IFN-alpha/beta R1 , Cytokine receptor class-II member 1 , beta-type antiviral protein , human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC , alpha-type antiviral protein
Interferon-alpha/beta receptor 1 (IFN- alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
TMPJ-00331