OGG1 Protein, Human, Recombinant

Product Overview

• Article Name: OGG1 Protein, Human, Recombinant
• Biozol Catalog Number: TGM-TMPJ-00457
• Supplier Catalog Number: TMPJ-00457
• Alternative Catalog Number: TGM-TMPJ-00457-1MG,TGM-TMPJ-00457-5UG,TGM-TMPJ-00457-10UG,TGM-TMPJ-00457-20UG,TGM-TMPJ-00457-50UG,TGM-TMPJ-00457-100UG,TGM-TMPJ-00457-200UG,TGM-TMPJ-00457-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: OGH1 , N-Glycosylase/DNA Lyase , DNA-(Apurinic or Apyrimidinic Site) Lyase , AP Lyase , MMH , 8-Oxoguanine DNA Glycosylase , MUTM , OGG1

Product Description

Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a beta-lyase activity that nicks DNA 3 to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma.

Images

TMPJ-00457