QPRTase Protein, Human, Recombinant (His)

Product Overview

• Article Name: QPRTase Protein, Human, Recombinant (His)
• Biozol Catalog Number: TGM-TMPJ-00473
• Supplier Catalog Number: TMPJ-00473
• Alternative Catalog Number: TGM-TMPJ-00473-1MG,TGM-TMPJ-00473-5UG,TGM-TMPJ-00473-10UG,TGM-TMPJ-00473-20UG,TGM-TMPJ-00473-50UG,TGM-TMPJ-00473-100UG,TGM-TMPJ-00473-200UG,TGM-TMPJ-00473-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: QPRTase , QAPRTase , Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating] , QPRT , Quinolinate Phosphoribosyltransferase [Decarboxylating]

Product Description

Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.

Images

TMPJ-00473