PDI5 , PADI4 , Protein-arginine Deiminase type IV , HL-60 PAD , PADI5 , Protein-Arginine Deiminase Type-4 , Peptidylarginine Deiminase IV
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
Purity:
95.00%
TMPJ-00532
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