Leukocyte immunoglobulin-like receptor subfamily A member 3 , ILT-6 , LIR-4 and Monocyte inhibitory receptor HM43/HM31 , Leukocyte immunoglobulin-like receptor 4 , Immunoglobulin-like transcript 6 , CD85 antigen-like family member E
Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung.
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