TNFAIP4 , LERK1 , Tumor Necrosis Factor alpha-Induced Protein 4 , Immediate Early Response Protein B61 , Ephrin-A1 , TNF Alpha-Induced Protein 4 , EFNA1 , EPLG1 , TNF alpha-Induced Protein 4 , Tumor Necrosis Factor Alpha-Induced Protein 4 , LERK-1 , EPH-Related Receptor Tyrosine Kinase Ligand 1
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.
Purity:
0.85
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