Bc1-w Protein, Human, Recombinant (His)

Product Overview

• Article Name: Bc1-w Protein, Human, Recombinant (His)
• Biozol Catalog Number: TGM-TMPJ-00584
• Supplier Catalog Number: TMPJ-00584
• Alternative Catalog Number: TGM-TMPJ-00584-1MG,TGM-TMPJ-00584-5UG,TGM-TMPJ-00584-10UG,TGM-TMPJ-00584-20UG,TGM-TMPJ-00584-50UG,TGM-TMPJ-00584-100UG,TGM-TMPJ-00584-200UG,TGM-TMPJ-00584-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Apoptosis Regulator Bcl-W , KIAA0271 , Bcl-2-Like Protein 2 , Bcl2-L-2 , BCLW , BCL2L2

Product Description

Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.

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TMPJ-00584