Complement C8 gamma Protein, Human, Recombinant (His)

Product Overview

• Article Name: Complement C8 gamma Protein, Human, Recombinant (His)
• Biozol Catalog Number: TGM-TMPJ-00585
• Supplier Catalog Number: TMPJ-00585
• Alternative Catalog Number: TGM-TMPJ-00585-1MG,TGM-TMPJ-00585-5UG,TGM-TMPJ-00585-10UG,TGM-TMPJ-00585-20UG,TGM-TMPJ-00585-50UG,TGM-TMPJ-00585-100UG,TGM-TMPJ-00585-200UG,TGM-TMPJ-00585-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: C8 gamma , Complement component C8 gamma chain , C8G , Complement component C8 gamma chain

Product Description

Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.

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TMPJ-00585