BAG-2 , BAG Family Molecular Chaperone Regulator 2 , BAG2 , Bcl-2-Associated Athanogene 2
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Purity:
97.85%
TMPJ-00717
* VAT and and shipping costs not included. Errors and price changes excepted
