HLA class II histocompatibility antigen gamma chain , HLA-DR antigens-associated invariant chain , HLA class II histocompatibility antigen gamma chain , Cluster of Differentiation 74 , CD74
Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
TMPJ-00775
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