CIA , Anti-Silencing Function Protein 1 Homolog A , ASF1A , Histone Chaperone ASF1A , CCG1-Interacting Factor A , hCIA , hAsf1 , hAsf1a
Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Molecular Weight:
22 KDa (reducing condition)
TMPJ-01399
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