Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo) is expressed in E. coli expression system with N-His-Sumo tag. The predicted molecular weight is 22.9 kDa and the accession number is O43927.
Molecular Weight:
22.9 kDa (predicted). The protein migrates to 26-28 kDa based on Tris-Bis PAGE result.
TMPK-00018
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