LEP , Obesity factor , Leptin , LEPD , Obese protein , OBS , OB
Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenital leptin deficiency (CLD) due to mutations in the leptin gene.
Molecular Weight:
42.76 kDa (predicted). Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
TMPK-00050
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