CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 50.9 kDa and the accession number is Q5QGZ9-2.
Molecular Weight:
50.9 kDa (predicted). Due to glycosylation, the protein migrates to 68-73 kDa based on Tris-Bis PAGE result.
TMPK-01004
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