TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)

Product Overview

• Article Name: TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)
• Biozol Catalog Number: TGM-TMPK-01382
• Supplier Catalog Number: TMPK-01382
• Alternative Catalog Number: TGM-TMPK-01382-5UG,TGM-TMPK-01382-10UG,TGM-TMPK-01382-20UG,TGM-TMPK-01382-50UG,TGM-TMPK-01382-100UG,TGM-TMPK-01382-200UG,TGM-TMPK-01382-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: p75TNFR , p75TBPII , CD120b , TNF-R75 , TNFR1B , TNFR2 , TNF-R2 , Etanercept , TBPII , TNFRSF1B , TNFBR , TNF RII , TNFR80

Product Description

Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Images

TMPK-01382