ASGR2 Protein, Human, Recombinant (His)

Product Overview

• Article Name: ASGR2 Protein, Human, Recombinant (His)
• Biozol Catalog Number: TGM-TMPY-02909
• Supplier Catalog Number: TMPY-02909
• Alternative Catalog Number: TGM-TMPY-02909-1MG, TGM-TMPY-02909-5UG, TGM-TMPY-02909-10UG, TGM-TMPY-02909-20UG, TGM-TMPY-02909-50UG, TGM-TMPY-02909-100UG, TGM-TMPY-02909-200UG, TGM-TMPY-02909-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: ASGP-R2 , HBXBP , ASGPR2 , HL-2 , asialoglycoprotein receptor 2 , CLEC4H2

Product Description

ASGR2 is a subunit of the asialoglycoprotein receptor. Asialoglycoprotein receptor, also known as the Ashwell receptor, which is specific for desialylated (galactosyl-terminal) glycoproteins and is expressed exclusively in hepatic parenchymal cells. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. ASGR2 is a glycoprotein. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit.