CAMKII alpha/CAMK2A Protein, Human, Recombinant (GST)

Product Overview

• Article Name: CAMKII alpha/CAMK2A Protein, Human, Recombinant (GST)
• Biozol Catalog Number: TGM-TMPY-04373
• Supplier Catalog Number: TMPY-04373
• Alternative Catalog Number: TGM-TMPY-04373-10UG, TGM-TMPY-04373-20UG, TGM-TMPY-04373-50UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: calcium/calmodulin-dependent protein kinase II alpha , calcium/calmodulin-dependent protein kinase II alpha , CAMKA , CaMKII alpha/CAMK2A

Product Description

Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily. CaM kinase II is thought to be an important mediator of learning and memory and is also necessary for Ca2+homeostasis and reuptake in cardiomyocytes chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CAMKIIA is one of the major forms of CAMKII. It has been found to play a critical role in sustaining activation of CAMKII at the postsynaptic density. Studies have found that knockout mice without CAMKIIA demonstrate a low frequency of LTP. Additionally, these mice do not form persistent, stable place cells in the hippocampus.