Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)

Product Overview

• Article Name: Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)
• Biozol Catalog Number: TGM-TMPY-04406
• Supplier Catalog Number: TMPY-04406
• Alternative Catalog Number: TGM-TMPY-04406-10UG, TGM-TMPY-04406-20UG, TGM-TMPY-04406-50UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: PKD2 , HSPC187 , nPKC-D2 , protein kinase D2

Product Description

Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is widely expressed. It contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. PRKD2 / PKD2 is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains bind DAG, mediating translocation to membranes. Autophosphorylation of Ser-71 and phosphorylation of Ser-76 by PKC relieves auto-inhibition by the PH domain. PRKD2 / PKD2 converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.