Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Abeta toxicity, which decreases Abeta deposition by decreasing the expression of Abeta at the mRNA level. Qingyangshengenin B has antiepileptic and anti-aging effects, it can extend lifespan, increase heat stress-resistance, delay body paralysis, and increase the chemotaxis response in C. elegans models of Alzheimers disease. Otophylloside B can suppress the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.
Molecular Weight:
923.13
Purity:
99.51%
CAS Number:
[106758-54-7]
Formula:
C49H78O16
Target:
Beta Amyloid
TMS1461
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