Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear translocation of p65 subunit of NF-kappaB. It also exhibits antiallergic effects without affecting the viability of bone marrow-derived mast cells.
Molecular Weight:
416.46
CAS Number:
[1134188-26-3]
Formula:
C23H28O7
Target:
Prostaglandin Receptor|||NF-kappaB|||NO Synthase
TN1009
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