Glabranine is a natural prenylated flavonoid isolated from Tephrosia species that exhibits potent inhibitory activity against the Dengue virus (DENV) in vitro. Its primary mechanism involves interacting with the soluble ectodomain of the DENV type 2 (DENV2) Envelope (E protein), potentially blocking viral entry or membrane fusion. The presence of the prenyl group is considered essential for its biological potency, making it a valuable scaffold for flavivirus-targeted drug discovery.
Molecular Weight:
324.37
CAS Number:
[41983-91-9]
Formula:
C20H20O4
Target:
Virus Protease
TN1689
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