1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cgamma-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines.
Molecular Weight:
350.41
CAS Number:
[1286694-67-4]
Formula:
C19H26O6
Target:
NO Synthase|||STAT|||JNK|||JAK|||IL Receptor|||Caspase|||ROS|||MAPK|||PARP
TN2511
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