4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by modulating splicing factors and histone modifications.4bHWE is a useful natural anti-inflammatory compound to attenuate progression of diabetes and obesity, it decreases inflammatory responses by inhibiting the NF-iB signaling in diabetic mouse adipose tissue, it also can improve impaired glucose tolerance.
Molecular Weight:
502.604
CAS Number:
[54334-04-2]
Formula:
C28H38O8
Target:
PARP|||COX|||NF-kappaB|||HSP|||PPAR
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