Aphadilactone C shows significant antimalarial activity with the IC50 value of 170 10 nM. It shows potent and selective inhibition against the diacylglycerol O-acyltransferase-1 (DGAT-1) enzyme (IC50 = 0.46 0.09 uM, selectivity index > 217).
Molecular Weight:
660.84
CAS Number:
[1522004-70-1]
Formula:
C40H52O8
Target:
Parasite|||Others|||Acyltransferase
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