Damulin A is an active dammarane-type saponin isolated from Gynostemma pentaphyllum and belongs to a group of structurally related compounds whose anticancer structure-activity relationships have been deeply explored. Comparative investigations reveal that double bonds positioned at C20(21) and C20(22) and hydroxyl modification at C-2 significantly contribute to cytotoxicity, as evidenced by proliferation inhibition in A549 cells. These findings confirm the importance of Damulin A within the broader context of Gynostemma-derived anticancer leads.
Molecular Weight:
783.01
Purity:
98.33%
CAS Number:
[1202868-74-3]
Formula:
C42H70O13
Target:
Others
TN3758
TN3758
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