Isoangustone A is a natural product that inhibits PI3K, MKK4, and MKK7 through ATP competition, suppresses the expression of G1 phase regulatory proteins, inhibits the phosphorylation of Akt, GSK-3beta, and JNK1/2, and inhibits the proliferation of human melanoma cells and tumour growth in xenograft mouse models.
Molecular Weight:
422.47
Purity:
98.89%
CAS Number:
[129280-34-8]
Formula:
C25H26O6
Target:
JNK|||Apoptosis|||Autophagy|||MAPK|||PI3K
TN4263
TN4263
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