Chlorahololide D is a natural lindane-type sesquiterpene dimer and selective potassium channel blocker that stimulates reactive oxygen species ROS levels to cause cell cycle arrest in the G2 phase, modulates Bcl-2 and Bax and FAK, thereby inhibiting MCF-7 cell growth and triggering apoptosis. Chlorahololide D inhibits tumor proliferation, migration and angiogenesis in in vivo experiments and has anti-breast cancer potential.
Molecular Weight:
676.75
Purity:
98.43%
CAS Number:
[943136-39-8]
Formula:
C38H44O11
Target:
Bcl-2 Family|||Potassium Channel|||FAK
TN5335
TN5335
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