Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and extrinsic pathway, followed by downstream events leading to apoptotic cell death, it could therefore, serve as a useful agent to treat human advanced prostate cancer.
Molecular Weight:
349.434
CAS Number:
[111768-16-2]
Formula:
C21H23N3O2
Target:
PPAR|||Apoptosis|||Caspase
TN6059
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