Alisol B acetate can induce Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells, the Bax activation and translocation from the cytosol to nucleus might be a crucial response to the apoptotic effect. Alisol B acetate exhibits an antiproliferative effect in SGC7901 cells by inducing apoptosis, apoptosis of SGC7901 cells involves mitochondria-caspase and PI3K/Akt dependent pathways.
Molecular Weight:
514.74
CAS Number:
[19865-76-0]
Formula:
C32H50O5
Target:
Akt|||Caspase|||PI3K|||Apoptosis
TN6394
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