Isololiolide has phytotoxicity, it inhibited seedling growth of cress and barnyard grass. It also showed in vitro activity against both trypomastigote and intracellular amastigotes of Trypanosoma cruzi, with IC50 values of 32 µM and 40 µM, respectively. Isololiolide is an antioxidant response element (ARE) inducer, it has anti-inflammatory activity. It can exert a selective cytotoxic activity on hepatocarcinoma HepG2 cells as well as induce apoptosis through the modulation of apoptosis-related proteins.
Molecular Weight:
196.24
CAS Number:
[38274-00-9]
Formula:
C11H16O3
TN6501
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