Ardeemin ((-)-Ardeemin) binds to P-glycoprotein, inhibiting the efflux of anticancer drugs from cells. In breast cancer xenograft models, Ardeemin can reverse the multidrug resistance phenotype of tumor cells and enhance their sensitivity to anticancer drugs.
Molecular Weight:
426.51
CAS Number:
[148441-25-2]
Formula:
C26H26N4O2
Target:
P-gp
TN9034
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