rel-(2R,3R)-Nitric oxide production-IN-11k, CAS [[1010705-14-2]]

Product Overview

• Article Name: rel-(2R,3R)-Nitric oxide production-IN-11k, CAS [[1010705-14-2]]
• Biozol Catalog Number: TGM-TN9824
• Supplier Catalog Number: TN9824
• Alternative Catalog Number: TGM-TN9824-1MG, TGM-TN9824-5MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: rel-(2S,3S)-Nitric oxide production-IN-11k

Product Description

rel-(2R,3R)-Nitric oxide production-IN-11k is an isomer of Nitric oxide production-IN-11k (T206206). Nitric oxide production-IN-11k is a compound that exerts anti-inflammatory effects by inhibiting the TLR4, JNK, and NF-kappaB signaling pathways. Nitric oxide production-IN-11k suppresses nitric oxide (NO) production in LPS-stimulated RAW264.7 cells, with an IC50 of 23.2 µM. The mechanism of action involves downregulation of TLR4 expression, inhibition of JNK phosphorylation, and suppression of NF-kappaB activation, thereby reducing the expression of iNOS and COX-2 and consequently decreasing the production of inflammatory mediators such as NO, PGE2, and TNF-alpha.

Product Properties

• Molecular Weight: 344.4
• CAS Number: [1010705-14-2]
• Formula: C23H20O3
• Target: TLR

Images

TN9824