2-O-Methyl-5-iodouridine (5-Iodo-2-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity. The anticancer mechanism of 2-O-Methyl-5-iodouridine is dependent on the inhibition of DNA synthesis and induction of apoptosis.