Potent and selective human formyl peptide receptor FPR2 agonist (EC50 values are 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Induces migration of human monocytes and neutrophils via a chemotactic mechanism and enhances production of proinflammatory cytokines IL-1beta and IL-6. Also activates the neutrophil superoxide-generating NADPH-oxidase.
Molecular Weight:
1610.97
CAS Number:
[271246-66-3]
Formula:
C75H123N19O18S
Target:
Calcium Channel
TP1891
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