P110 heptapeptide is a specific peptide inhibitor that interacts with Drp1/Fis1 (IC50=1.8 µM). By competitively blocking the binding of Drp1 to Fis1, P110 heptapeptide inhibits pathological mitochondrial fission while preserving the physiological function of Drp1, thereby reducing pathological features in numerous models of neurodegeneration, ischemia, and sepsis. P110 heptapeptide exhibits neuroprotective, anti-inflammatory, and anti-sepsis activity and can be used in research on neurodegenerative diseases and conditions associated with mitochondrial dysfunction.
Molecular Weight:
2411.8
CAS Number:
[1411976-18-5]
Formula:
C100H179N45O25
Target:
Others
TP1947
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