Potent endogenous ligand of the kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with Ki values of 1.80 and 1.45 nM respectively. Inhibits chemotaxis, invasion and metastasis of human melanomas and breast carcinomas. Stimulates gonadotropin secretion following i.c.v. administration.
Molecular Weight:
5857.49
CAS Number:
[374683-24-6]
Formula:
C258H401N79O78
Target:
GNRH Receptor
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