GluN2B (formally NR2B) selective, competitive antagonist of the NMDA receptor. Blocks NMDA-evoked current in mouse cortical neurons (IC50 = 480 nM), also inhibits NMDA-evoked responses in oocytes expressing GluN2B (formally NR2B), but not GluN2A (formally NR2A), subunits (IC50 ~300 nM). Exhibits neuroprotective properties in vivo and in vitro.
Molecular Weight:
2264.21
CAS Number:
[93438-65-4]
Formula:
C88H138N26O44
Target:
iGluR
TP2060
* VAT and and shipping costs not included. Errors and price changes excepted