TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent CXCR7 agonist with an EC50 of 350 nM for recruiting beta-arrestin 2 to CXCR7. TC14012 has anti-cancer activity and anti-HIV activity.
Molecular Weight:
2126.47
Purity:
98.33%
Formula:
C92H144N34O21S2
Target:
CXCR|||Arrestin
TP2112L
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