A20FMDV2 is a highly selective alphavbeta6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for alphavbeta6 compared to other RGD-directed integrins like alphavbeta3, alphavbeta5, and alpha5beta1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of alphavbeta6 integrin-positive tumors.
Molecular Weight:
2163.48
CAS Number:
[932699-03-1]
Formula:
C93H163N31O28
Target:
Integrin
TP2698
TP2698
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