BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.
Molecular Weight:
1308.52
CAS Number:
[1629625-47-3]
Formula:
C52H93N25O13S
Target:
COX|||IFNAR|||Interleukin
TP2930
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