cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.
Molecular Weight:
3612.12
CAS Number:
[2853605-24-8]
Formula:
C146H232N52O44S6
Target:
Factor Xa
TP2974
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