PKHB1 is a thrombospondin-1 peptide mimetic known for its antitumor properties. It induces mitochondrial alterations, ROS generation, intracellular Ca+ accumulation, and calcium-dependent cell death in breast cancer cells. Additionally, PKHB1 promotes immune system activation through immunogenic cell death in breast cancer cells.
Molecular Weight:
1384.73
CAS Number:
[1505523-99-8]
Formula:
C68H105N17O12S
Target:
Thrombopoietin Receptor|||Reactive Oxygen Species
TP2999
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