MAIT-203 acetate is a cyclopentylglycine-derived peptidomimetic that effectively inhibits the interaction between adenomatous polyposis coli (APC) and Asef (RhoGEF4), while not affecting the APC-Sam68 or APC-striatin interactions. It binds to APC-ARM with a Ki of 0.015 µM and a Kd of 0.036 µM, significantly impeding the migration and invasion of colorectal cancer cells.
Molecular Weight:
2517.85 (free base)
Formula:
C108H121N43O31
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