HL2-m5 is an inhibitor of the sonic hedgehog/patched (Shh/PTCH1) interaction, with a Kd for Shh of 170 nM. It effectively inhibits the activation of the Hedgehog signaling pathway and the transcription of Gli-controlled genes, with an IC50 of 230 nM.
Molecular Weight:
1632.83
CAS Number:
[2130846-15-8]
Formula:
C70H101N15O24S3
Target:
Hedgehog/Smoothened
TP3102
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