TAT-N15, a p55PIK inhibitor, demonstrates significant anti-inflammatory and neuroprotective effects. It effectively suppresses the activation of IL-6, IL-8, Akt, and NF-kappaB pathways, along with the phosphorylation of STAT3 and the protein expression of NF-kappaB. TAT-N15 is applicable for research on acute conjunctivitis, allergic rhinitis, chronic obstructive pulmonary disease (COPD), and stroke through its inhibition of Akt, STAT3, and NF-kappaB pathways.
Molecular Weight:
3522.14
CAS Number:
[2415370-74-8]
Formula:
C155H250N48O40S3
Target:
NF-kappaB|||STAT|||Akt|||Interleukin
TP3106
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