PDpep1.3 is a peptide inhibitor targeting alpha-synuclein, which disrupts the direct interaction between alpha-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B). This disruption enables PDpep1.3 to restore the degradative functions of endosomes and lysosomes, reducing the levels and aggregation of alpha-synuclein, and safeguarding dopaminergic neurons from alpha-synuclein-induced degeneration. PDpep1.3 is useful for research on neurodegenerative diseases and protein-protein interactions.
Molecular Weight:
1400.53
CAS Number:
[2942277-55-4]
Formula:
C59H101N17O22
Target:
Others
TP3573
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